genediag

Conjugation Site Influences Antibody-Conjugated Drug PK Assays: Case Studies for Disulfide-Linked, Self-Immolating Next-Generation Antibody Drug Conjugates

 

Immunoaffinity (IA) LC-MS/MS pharmacokinetic (PK) assays are widely used in the field for antibody drug conjugates (ADCs) containing peptide linkers that are enzymatically cleavable, such as MC-ValCit-PAB. Conjugate PK assay strategies for these ADCs involve cleavage with cathepsin B or papain to release and measure the antibody-conjugated drug (acDrug) concentration.
However, robust acDrug PK methods for disulfide-linked self-immolating ADCs are lacking as they are a different conjugation modality. We developed acDrug PK assays for next-generation disulfide-linked ADCs involving immunoaffinity capture, chemical cleavage, and LC-MS/MS. Disulfide-linked ADCs captured from plasma were chemically reduced at basic pH to release the linker-drug, followed by self-immolation to liberate the active drug, and quantified by MRM LC-MS/MS.
Herein, we detail the development and optimization of this chemical cleavage acDrug PK assay, resulting in robust accuracy and precision (<u>+</u>20%). The conjugation site of the linker-drug on the antibody was found to affect the kinetics of drug release.
Multiple biophysical and chemical characteristics, such as tertiary structure, fractional solvent accessibility, pKa of the conjugation site, surrounding residue’s pI, and electrostatic charge, may directly impact the drug release kinetics. Similar site-specific stability has been previously reported for ADCs in vivo.
The assay development and qualification data for this original assay format are presented along with its application to multiple in vitro and in vivo studies across species.

Gestational Dysfunction-Driven Diets and Probiotic Supplementation Correlate with the Profile of Allergen-Specific Antibodies in the Serum of Allergy Sufferers

Background: Maternal diet has significant effects on development of childhood atopic disease and hypersensitivity development. However, the gestational dysfunctions demanding special diets are becoming a widespread phenomenon, their immunological implications can be manifested in the profile of antibodies in the offspring’s serum.
Methods: 153 allergic and 150 healthy individuals were diagnosed for allergy using specific antibody and cytokine immunoassay tests. The medical history of subjects along with mothers’ course of pregnancy was completed by allergologist’s anamnesis. A self-organizing neural network and multivariate analyses to complex data and pick basic interactions were used.
Results: Two significant explanatory modules were determined. The first was formed by gestational diabetic and cholestatic diet, infant formula feeding type, probiotic supplementation and its BMI index, moderate IgE, increased IgG levels of antibodies and single or poly-food allergy type (7 clusters).
The second was formed by gestational vegan/vegetarian and elimination diet, maternal probiotic supplementation, sex, high IgE total antibodies and food and mixed poly-allergy to aero- and food-origin allergens (19 clusters).
Conclusions: Significant associations were observed between special gestational diet intake underlying foetal programming and the mechanisms of childhood allergy. The novelty is the positive association between diabetic and cholestatic diet intake and IgE/IgG-mediated food hypersensitivity.
Keywords: allergic patterns; allergy prevalence; artificial self-organizing neural network; foetal programming; gestational dysfunction-driven diets; probiotics supplementation; specific IgE-antibodies profile.
genediag

genediag

Anti-human TNF-alpha antibody

STJ15100115 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of human TNF-α in Flow cytometry and Western blot.

Anti-human TNF-alpha antibody

STJ15100116 250 µg
EUR 336
Description: We recommend MT25C5 as capture antibody in ELISA and ELISpot in combination with biotinylated detection antibody MT20D9.

Anti-human TNF-alpha antibody

STJ15100117 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of human TNF-α in immunoassays such as ELISA and ELISpot.

Anti-TNF alpha Purified

11-687-C025 0.025 mg
EUR 99

Anti-TNF alpha Purified

11-687-C100 0.1 mg
EUR 158

Anti-TNF alpha Purified

11-688-C025 0.025 mg
EUR 99

Anti-TNF alpha Purified

11-688-C100 0.1 mg
EUR 158

Anti-TNF alpha APC

1A-688-T025 25 tests
EUR 140

Anti-TNF alpha APC

1A-688-T100 100 tests
EUR 240

Anti-TNF alpha FITC

1F-688-T025 25 tests
EUR 122

Anti-TNF alpha FITC

1F-688-T100 100 tests
EUR 204

Anti-TNF alpha PE

1P-688-T025 25 tests
EUR 140

Anti-TNF alpha PE

1P-688-T100 100 tests
EUR 240

Anti-TNF alpha Antibody

A00002-2 100ug/vial
EUR 294

Anti-TNF alpha Antibody

A00002-3 100ug/vial
EUR 294

anti- TNF alpha antibody

FNab08815 100µg
EUR 585
  • Recommended dilution: WB: 1:500-1:5000
  • IHC: 1:200-1:1000
  • Immunogen: tumor necrosis factor(TNF superfamily, member 2)
  • Uniprot ID: P01375
  • Research Area: Signal Transduction, Cardiovascular, Cancer, Immunology, Neuroscience
Description: Antibody raised against TNF alpha

anti- TNF-alpha antibody

FNab08821 100µg
EUR 585
  • Recommended dilution: WB: 1:200-1:1000
  • IHC: 1:50-1:500
  • Immunogen: tumor necrosis factor(TNF superfamily, member 2)
  • Uniprot ID: P01375
  • Research Area: Immunology, Cardiovascular, Developmental biology, Signal Transduction
Description: Antibody raised against TNF-alpha

anti- TNF alpha antibody

FNab09822 100µg
EUR 548.75
  • Recommended dilution: WB: 1:1000 - 1:2000
  • IHC: 1:50 - 1:100
  • Immunogen: tumor necrosis factor (TNF superfamily, member 2)
  • Uniprot ID: P01375
  • Gene ID: 7124
  • Research Area: Signal Transduction, Cardiovascular, Cancer, Immunology, Neuroscience
Description: Antibody raised against TNF alpha

Anti-TNF alpha Antibody

PA1079 100ug/vial
EUR 334

anti-TNF-alpha (2A9B9)

LF-MA30138 100 ul
EUR 486
Description: Mouse Monoclonal to TNF-alpha

anti- TNF alpha antibody

LSMab09822 100 ug
EUR 386

Anti-TNF-alpha antibody

PAab08821 100 ug
EUR 412

Anti-TNF alpha Antibody

PB9010 100ug/vial
EUR 294

Anti-TNF alpha Antibody

PB9246 100ug/vial
EUR 294

Anti-TNF alpha antibody

STJ140123 150 µg
EUR 408
Description: Goat polyclonal antibody to TNF alpha. TNF-alpha is produced by a variety of immune cells including NK cells, B cells, T cells and macrophages. It is multifunctional proinflammatory cytokine that belongs to the tumour necrosis factor (TNF) superfamily. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is involved in the regulation of several processes including lipid metabolism cell differentiation and proliferation, coagulation and apoptosis. It has been implicated in a variety of diseases, including cancer and autoimmune diseases.

Anti-TNF-Alpha antibody

STJ16100927 100 µg
EUR 451

Anti-TNF-Alpha antibody

STJ16100932 100 µg
EUR 648

Anti-TNF-Alpha antibody

STJ16100933 50 µg
EUR 531

Anti-TNF-Alpha antibody

STJ16100934 100 µg
EUR 648

Anti-TNF-Alpha antibody

STJ16100935 50 µg
EUR 531

Anti-TNF-alpha antibody

STJ96054 200 µl
EUR 197
Description: TNF-alpha is a protein encoded by the TNF gene which is approximately 25,6 kDa. TNF-alpha is localised to the cell membrane. It is involved in PEDF induced signalling, TNFR1 pathway, allograft rejection and apoptosis modulation and signalling. It is a cytokine that is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, lipid metabolism, and coagulation. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF-alpha is expressed in the blood, lung, spleen, liver and heart. Mutations in the TNF gene may result in psoriatic arthritis. STJ96054 was affinity purified. This polyclonal antibody binds to endogenous TNF-alpha.

Anti-TNF-alpha antibody

STJ96516 200 µl
EUR 197
Description: Rabbit polyclonal to TNF-alpha.

Anti-TNF alpha antibody

STJ97488 200 µl
EUR 197
Description: Rabbit polyclonal to TNF alpha.

Anti-TNF alpha antibody

STJ97489 200 µl
EUR 197
Description: Rabbit polyclonal to TNF alpha.

Anti-TNF alpha antibody

STJ97493 200 µl
EUR 197
Description: Mouse monoclonal to TNF alpha.

Anti-TNF alpha antibody

STJ97494 200 µl
EUR 197
Description: Mouse monoclonal to TNF alpha.

Monoclonal Anti-Human Tumor Necrosis Factor-Alpha (TNF-alpha) IgG #1 aff. Pure

TNFA11-M 100 ug
EUR 482

Monoclonal Anti-Human Tumor Necrosis Factor-Alpha (TNF-alpha) IgG #2, aff. Pure

TNFA12-M 100 ug
EUR 482

Rabbit Anti-Rat TNF-alpha Converting Enzyme (TACE) antiserum

TACE11-S 100 ul
EUR 457

Goat Anti-Human Tumor Necrosis Factor-Alpha (TNF-alpha) IgG #2, aff. Pure (neutralzing)

TNFA13-A 100 ul
EUR 482

Anti-human/monkey TNF-alpha antibody

STJ15100118 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of monkey TNF-α in immunoassays such as ELISA and ELISpot.

Anti-human/monkey TNF-alpha antibody

STJ15100119 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of TNF-α in immunoassays such as ELISA and ELISpot, Flow cytometry, and Western blot.

Anti-mouse TNF alpha Antibody

RP1000 100ug/vial
EUR 334

Anti-mouse TNF-alpha antibody

STJ15100113 250 µg
EUR 336
Description: These monoclonal antibodies enable sensitive and specific detection of mouse TNF-α in immunoassays such as ELISA and ELISpot.

Anti-mouse TNF-alpha antibody

STJ15100114 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of mouse TNF-α in immunoassays such as ELISA and ELISpot.

Anti-Mouse TNF-alpha antibody

STJ16100926 100 µg
EUR 701

Anti-Mouse TNF-alpha antibody

STJ16101171 1 mL
EUR 801

Anti-TNF alpha (M1-C4)

YF-MA10949 100 ug
EUR 363
Description: Mouse monoclonal to TNF alpha

Anti-TNF alpha (M2-E3)

YF-MA15915 100 ug
EUR 363
Description: Mouse monoclonal to TNF alpha

Human TNF-alpha ELISA Kit, 96 tests, Quantitative

100-215-TNH 1 kit
EUR 482

TNF alpha

GT15064 100 ug
EUR 526

TNF alpha

GT15113 100 ug
EUR 526

TNF-alpha

PR27146 50 ug
EUR 318

Rabbit Anti-Rat TNF-alpha Converting Enzyme (TACE), IgG aff. Pure

TACE11-A 100 ug
EUR 482

Anti-TNF alpha (Humicade), Human IgG4 Antibody

A1093-200
EUR 729

Anti-TNF alpha (Infliximab), Human IgG1 Antibody

A1097-200
EUR 778

Human anti TNF Alpha autoantibody ELISA kit

E01A2132-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A sandwich ELISA for quantitative measurement of Human anti TNF Alpha autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human anti TNF Alpha autoantibody ELISA kit

E01A2132-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Human anti TNF Alpha autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human anti TNF Alpha autoantibody ELISA kit

E01A2132-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Human anti TNF Alpha autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Recombinant (E.Coli) purified human Tumor Necrosis Factor-Alpha (TNF-alpha), biologically active

TNFA15-R-10 10 ug
EUR 225

Anti-TNF-alpha Antibody Clone TNF/1500R, Unconjugated-20ug

7124-RBM13-P0 20ug
EUR 233

Anti-TNF-alpha Antibody Clone TNF/1500R, Unconjugated-100ug

7124-RBM13-P1 100ug
EUR 428

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

TruStrip RDT Humira/Adalimumab (anti-TNF-alpha) Rapid Test cards, 10/pk

200-320-RDT 1 pk
EUR 293

Human TNF-alpha antibody

32809-05111 150 ug
EUR 261

TNF-alpha, human recombinant

1050-10
EUR 153

TNF-alpha, human recombinant

1050-1000
EUR 1751

TNF-alpha, human recombinant

1050-50
EUR 283

Human TNF-alpha Antibody

13101-05011 150 ug
EUR 217

Human TNF alpha Protein

abx060828-005mg 0.05 mg
EUR 551
  • Shipped within 5-10 working days.

TNF-alpha/TNFSF2, Human

HY-P7058 100ug
EUR 441

Anti-TNF alpha Purified Azide Free

10-687-C100 0.1 mg
EUR 158

Anti-TNF alpha (1C3-A1-F4)

YF-MA15914 100 ug
EUR 363
Description: Mouse monoclonal to TNF alpha

TNF-alpha Antibody

3052R-100
EUR 316

TNF-alpha Antibody

3052R-30T
EUR 146

TNF-alpha Antibody

3053R-100
EUR 316

TNF-alpha Antibody

3053R-30T
EUR 146

TNF-alpha Antibody

3054-100
EUR 316

TNF-alpha Antibody

3054-30T
EUR 146

TNF alpha protein

30R-2188 50 ug
EUR 532
Description: Purified recombinant Human TNF alpha protein

TNF alpha protein

30R-2317 50 ug
EUR 352
Description: Purified recombinant Human TNF alpha protein

TNF alpha protein

30R-2402 10 ug
EUR 247
Description: Purified recombinant Human TNF alpha protein

TNF alpha protein

30R-2403 10 ug
EUR 247
Description: Purified recombinant Human TNF alpha protein

Filling the Antibody Pipeline in Allergy: PIPE Cloning of IgE, IgG 1 and IgG 4 against the Major Birch Pollen Allergen Bet v 1

 

Birch pollen allergy is among the most prevalent pollen allergies in Northern and Central Europe. This IgE-mediated disease can be treated with allergen immunotherapy (AIT), which typically gives rise to IgG antibodies inducing tolerance. Although the main mechanisms of allergen immunotherapy (AIT) are known, questions regarding possible Fc-mediated effects of IgG antibodies remain unanswered.
This can mainly be attributed to the unavailability of appropriate tools, i.e., well-characterised recombinant antibodies (rAbs). We hereby aimed at providing human rAbs of several classes for mechanistic studies and as possible candidates for passive immunotherapy.
We engineered IgE, IgG1, and IgG4 sharing the same variable region against the major birch pollen allergen Bet v 1 using Polymerase Incomplete Primer Extension (PIPE) cloning. We tested IgE functionality and IgG blocking capabilities using appropriate model cell lines.
In vitro studies showed IgE engagement with FcεRI and CD23 and Bet v 1-dependent degranulation. Overall, we hereby present fully functional, human IgE, IgG1, and IgG4 sharing the same variable region against Bet v 1 and showcase possible applications in first mechanistic studies.
Furthermore, our IgG antibodies might be useful candidates for passive immunotherapy of birch pollen allergy.

LEC antibody

70R-LG003 50 ug
EUR 273
Description: Affinity purified Goat polyclonal LEC antibody

Recombinant Human LEC (CCL16) Protein

PROTO15467-1 20ug
EUR 317
Description: LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes but not neutrophils. Recombinant human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

LEC Chemokine(LEC66) Antibody

BNUB0066-100 100uL
EUR 209
Description: Primary antibody against LEC Chemokine(LEC66), Concentration: 0.2mg/mL

LEC Chemokine(LEC66) Antibody

BNUB0066-500 500uL
EUR 458
Description: Primary antibody against LEC Chemokine(LEC66), Concentration: 0.2mg/mL

LEC Chemokine(LEC67) Antibody

BNUB0067-100 100uL
EUR 209
Description: Primary antibody against LEC Chemokine(LEC67), Concentration: 0.2mg/mL

LEC Chemokine(LEC67) Antibody

BNUB0067-500 500uL
EUR 458
Description: Primary antibody against LEC Chemokine(LEC67), Concentration: 0.2mg/mL

LEC Chemokine(LEC66) Antibody

BNUM0066-50 50uL
EUR 395
Description: Primary antibody against LEC Chemokine(LEC66), 1mg/mL

LEC Chemokine(LEC67) Antibody

BNUM0067-50 50uL
EUR 395
Description: Primary antibody against LEC Chemokine(LEC67), 1mg/mL

LEC Chemokine(LEC66) Antibody

BNC040066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF405S conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC040066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF405S conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC040067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF405S conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC040067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF405S conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC610066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF660R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC610066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF660R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC610067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF660R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC610067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF660R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC470066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF647 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC470066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF647 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC470067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF647 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC470067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF647 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC550066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF555 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC550066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF555 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC550067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF555 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC550067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF555 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC050066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF405M conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC050066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF405M conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC050067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF405M conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC050067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF405M conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC400066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF640R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC400066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF640R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC400067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF640R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC400067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF640R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC430066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF543 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC430066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF543 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC430067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF543 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC430067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF543 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC800066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF680 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC800066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF680 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC800067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF680 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC800067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF680 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC810066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF680R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC810066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF680R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC810067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF680R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC810067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF680R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCP0066-250 250uL
EUR 383
Description: Primary antibody against LEC Chemokine(LEC66), PerCP conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCP0067-250 250uL
EUR 383
Description: Primary antibody against LEC Chemokine(LEC67), PerCP conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCR0066-250 250uL
EUR 383
Description: Primary antibody against LEC Chemokine(LEC66), RPE conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCR0067-250 250uL
EUR 383
Description: Primary antibody against LEC Chemokine(LEC67), RPE conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCA0066-250 250uL
EUR 383
Description: Primary antibody against LEC Chemokine(LEC66), APC conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCA0067-250 250uL
EUR 383
Description: Primary antibody against LEC Chemokine(LEC67), APC conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCAP0066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCAP0066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCAP0067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCAP0067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCH0066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCH0066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCH0067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCH0067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC940066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF594 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC940066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF594 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC940067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF594 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC940067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF594 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC700066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), CF770 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC700066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), CF770 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC700067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), CF770 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC700067-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC67), CF770 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCB0066-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC66), Biotin conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCB0066-500 500uL
EUR 544
Description: Primary antibody against LEC Chemokine(LEC66), Biotin conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCB0067-100 100uL
EUR 199
Description: Primary antibody against LEC Chemokine(LEC67), Biotin conjugate, Concentration: 0.1mg/mL