Bnp Assay Is For

PARPtrap™ Combo Assay Kit for PARP1 and PARP2

78317 384 rxns.
EUR 3000
Description: The PARPtrap™ Combo Assay Kit for PARP1 and PARP2 is a kit designed to measure DNA complex formations of PARP1 and PARP2 enzymes in a high throughput screening assay using fluorescence polarization (FP). The key to the PARPtrap™ Combo Assay Kit are the fluorescent-labeled DNA probes recognized by PARP1 and PARP2. In the absence of ribosylation, PARP1/2 binds to the DNA fluorescent probe, forming a large complex and resulting in the emission of highly polarized light. However, after autoribosylation, PARP1/2 dissociates from the oligonucleotide duplex, which then rotates freely, emitting less polarized light (Fig. 1). Addition of a PARP inhibitor results in trapping of PARP1/2 to the fluorescent-labeled DNA, and increases the FP signal in a dose dependent manner.The combo kit is particularly useful to directly and specifically compare, in a single assay, the effect and potency of a compound on PARP1 and PARP2. The PARPtrap™ Combo Assay Kit for PARP1 and PARP2 is a homogeneous fluorescence polarization assay. The FP signal is measured using a fluorescent microplate reader capable of measuring fluorescence polarization.

Bnp Assay Laboratories manufactures the bnp assay is for reagents distributed by Genprice. The Bnp Assay Is For reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact bnp assay. Other Bnp products are available in stock. Specificity: Bnp Category: Assay Group: Is For

PARPtrap™ Assay Kit for PARP2

384 rxns.
EUR 3070
Description: The PARPtrap™ Assay Kit for PARP2 is designed to measure PARP2/DNA complex formation in a high throughput screening assay using fluorescence polarization (FP). Similarly, to PARP1, PARP2 recognizes and binds damaged DNA via its DNA-binding domain. Binding to DNA activates PARP2 and in the presence of NAD+ PARP2 ribosylates itself (auto-ribosylation), which leads to PARP2 dissociation from the DNA due to the accumulated negative charge of the ribosyl polymer. In the presence of some inhibitors, however, PARP remains bound to the DNA, a phenomenon termed trapping. Trapped PARP-DNA complexes have been shown to be highly cytotoxic to cancer cells, therefore such inhibitors may be desirable for cancer treatment. The key to the PARPtrap™ Assay Kit is the fluorescent-labeled oligonucleotide duplex. In the absence of ribosylation, PARP2 binds to the fluorescent probe, forming a large complex and resulting in the emission of highly polarized light. However, after auto-ribosylation PARP2 dissociates from the oligonucleotide duplex, which then rotates freely, emitting less polarized light (Fig. 1). Addition of a PARP2 inhibitor results in trapping of PARP2 to the fluorescent oligonucleotide duplex, and increases the FP signal in a dose dependent manner.The PARPtrap™ Assay Kit is a fluorescence polarization homogeneous assay. The FP signal is measured using a fluorescent microplate reader capable of measuring fluorescence polarization.

Glycerol Assay Kit (For liquid samples)

1 Kit
EUR 735.6

PARPtrap™ Assay Kit for PARP1

96 rxns.
EUR 2145
Description: The PARPtrap™ Assay Kit for PARP1 is designed to measure PARP1/DNA complex formation in a high throughput screening assay using fluorescence polarization (FP). PARP1 is known to bind damaged DNA through its DNA-binding domains. Binding to DNA activates PARP1 and in the presence of NAD+ PARP1 ribosylates itself (auto-ribosylation), what in consequence leads to PARP1 dissociation from the DNA due to the accumulated negative charge of the ribosyl polymer. In the presence of some inhibitors, however, PARP remains bound to the DNA, a phenomenon termed trapping. Trapped PARP-DNA complexes have been shown to be highly cytotoxic to cancer cells, therefore such inhibitors may be desirable for cancer treatment.The key to the PARPtrap™ Assay Kit for PARP1 is the fluorescent-labeled oligonucleotide duplex. In the absence of ribosylation, PARP1 binds to the fluorescent probe, forming a large complex and resulting in the emission of highly polarized light. However, after auto-ribosylation, PARP1 dissociates from the oligonucleotide duplex, which then rotates freely, emitting less polarized light (Fig. 1). Addition of a PARP1 inhibitor results in trapping of PARP1 to the fluorescent oligonucleotide duplex, and increases the FP signal in a dose dependent manner.The PARPtrap™ Assay Kit for PARP1 is a fluorescence polarization homogeneous assay. The FP signal is measured using a fluorescent microplate reader capable of measuring fluorescence polarization.

PARPtrap™ Assay Kit for PARP1

384 rxns.
EUR 3070
Description: The PARPtrap™ Assay Kit for PARP1 is designed to measure PARP1/DNA complex formation in a high throughput screening assay using fluorescence polarization (FP). PARP1 is known to bind damaged DNA through its DNA-binding domains. Binding to DNA activates PARP1 and in the presence of NAD+ PARP1 ribosylates itself (auto-ribosylation), what in consequence leads to PARP1 dissociation from the DNA due to the accumulated negative charge of the ribosyl polymer. In the presence of some inhibitors, however, PARP remains bound to the DNA, a phenomenon termed trapping. Trapped PARP-DNA complexes have been shown to be highly cytotoxic to cancer cells, therefore such inhibitors may be desirable for cancer treatment.The key to the PARPtrap™ Assay Kit for PARP1 is the fluorescent-labeled oligonucleotide duplex. In the absence of ribosylation, PARP1 binds to the fluorescent probe, forming a large complex and resulting in the emission of highly polarized light. However, after auto-ribosylation, PARP1 dissociates from the oligonucleotide duplex, which then rotates freely, emitting less polarized light (Fig. 1). Addition of a PARP1 inhibitor results in trapping of PARP1 to the fluorescent oligonucleotide duplex, and increases the FP signal in a dose dependent manner.The PARPtrap™ Assay Kit for PARP1 is a fluorescence polarization homogeneous assay. The FP signal is measured using a fluorescent microplate reader capable of measuring fluorescence polarization.

DPA/Terbium for membrane fusion assay

KT
EUR 92

SDIP/Europium for membrane fusion assay

KT
EUR 151

AOPI Viability Assay for Flow Cytometry

5 mL
EUR 98

Is For information

Rat Brain Natriuretic Peptide 32 (BNP-32) AssayLite Antibody (APC Conjugate)

10541-05061 150 ug
EUR 513.6

Rat Brain Natriuretic Peptide 32 (BNP-32) AssayLite Antibody (PerCP Conjugate)

10541-05071 150 ug
EUR 565.2

Streptavidin-HRP (For PARP & Cytokine Assay Kits)

80611 100 µl
EUR 100
Description: Streptavidin-HRP is useful in select BPS Bioscience assay kits.

Micrococcus lysodeikticus, ATCC No.4698 for Lysozyme Assay

23372-14 5G
EUR 92.4

Hyperactive Universal CUT&Tag Assay Kit for Illumina

TD903-01 24 rxns
EUR 300

Hyperactive Universal CUT&Tag Assay Kit for Illumina

TD903-02 48 rxns
EUR 1114

QuDye dsDNA HS Assay kit (optimized for Qubit), 100

13102 100 assays
EUR 98.4

PARPtrap™ Combo Assay Kit for PARP1 and PARP2

78317 384 rxns.
EUR 3000
Description: The PARPtrap™ Combo Assay Kit for PARP1 and PARP2 is a kit designed to measure DNA complex formations of PARP1 and PARP2 enzymes in a high throughput screening assay using fluorescence polarization (FP). The key to the PARPtrap™ Combo Assay Kit are the fluorescent-labeled DNA probes recognized by PARP1 and PARP2. In the absence of ribosylation, PARP1/2 binds to the DNA fluorescent probe, forming a large complex and resulting in the emission of highly polarized light. However, after autoribosylation, PARP1/2 dissociates from the oligonucleotide duplex, which then rotates freely, emitting less polarized light (Fig. 1). Addition of a PARP inhibitor results in trapping of PARP1/2 to the fluorescent-labeled DNA, and increases the FP signal in a dose dependent manner.The combo kit is particularly useful to directly and specifically compare, in a single assay, the effect and potency of a compound on PARP1 and PARP2. The PARPtrap™ Combo Assay Kit for PARP1 and PARP2 is a homogeneous fluorescence polarization assay. The FP signal is measured using a fluorescent microplate reader capable of measuring fluorescence polarization.

Viability/Cytotoxity Assay Kit for Animal Live & Dead Cell (150 assays)

30002-T 1KIT
EUR 219.6
Description: Minimum order quantity: 1 unit of 1KIT

Viability/Cytotoxity Assay Kit for Animal Live & Dead Cell (150 assays)

30002-T-1 KT
EUR 150

Viability/Cytotoxity Assay Kit for Animal Live & Dead Cells (300 assays)

30002-1 KT
EUR 298

Pyrophosphate Assay Reagent for RNAP (enzyme not included)

PPA1000 1000 assays
EUR 372.78
Description: This product includes 3200 ul of Buffer RP, 310 ul of 100 x NTP mix, 310 ul of 100 x DNA, 32 ul of 1000 x pyrophosphatase and 42 ml of dye for 100 assays of E. coli RNA polymerase reactions in a 384-well assay format. The assay This product includes all reagents except the enzyme.

Anti-Cetuximab Antibody (AY27) (recommended for ADA assay)

CEB-Y27 100ug
EUR 2140
Description: Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Cetuximab F(ab')2.

Anti-Rituximab Antibody (AY36) (recommended for ADA assay)

RIB-Y36 100ug
EUR 2354
Description: Anti-Rituximab Antibodies (recommended for ADA assay) antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Rituximab.

Anti-Bevacizumab Antibody (AY9) (recommended for ADA assay)

BEB-Y9 100ug
EUR 2354
Description: Anti-Bevacizumab Antibodies (recommended for ADA assay) antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Bevacizumab.

Hyperactive pG-MNase CUT&RUN Assay Kit for Illumina

HD102-01 24 rxns
EUR 316.8

Live/Dead Cell Viability Assay Kit (for Mammalian Cells)

K502-100 each
EUR 548.4