August 24, 2020
Antibody against the CSP N-terminal domain lacks Plasmodium
A high-affinity antibody in opposition to the CSP N-terminal area lacks Plasmodium falciparum inhibitory exercise
Malaria is a world well being concern, and analysis efforts are ongoing to develop a superior vaccine to RTS,S/AS01. To information immunogen design, we search a complete understanding of the protecting humoral response in opposition to Plasmodium falciparum (Pf) circumsporozoite protein (PfCSP). In distinction to the well-studied responses to the repeat area and the C-terminus, the antibody response in opposition to the N-terminal area of PfCSP (N-CSP) stays obscure.
- Right here, we characterised the molecular recognition and practical efficacy of the N-CSP-specific monoclonal antibody 5D5.
- The crystal construction at 1.85-Å decision revealed that 5D5 binds an α-helical epitope in N-CSP with excessive affinity by means of in depth form and cost complementarity and the weird utilization of an antibody N-linked glycan.
- Nonetheless, practical research indicated low 5D5 binding to stay Pf sporozoites and lack of sporozoite inhibition in vitro and in vivo. General, our knowledge don’t assist the inclusion of the 5D5 N-CSP epitope into the following era of CSP-based vaccines.
Absence of YF-neutralizing antibodies in susceptible populations of Brazil: A warning for epidemiological surveillance and the potential dangers for future outbreaks
Yellow Fever (YF) is an acute febrile sickness brought on by yellow fever virus (YFV), a mosquito-borne flavivirus transmitted topeople and non-human primates. In Brazil, YF is a public well being risk and will trigger recurrent epidemics, even with the supply of a vaccine.
We evaluated the sero-status for YFV in 581 people dwelling in a danger space for YF in Brazil. The realm presents historical past of circumstances and is positioned within the southeast area of nation the place outbreaks of YF have been reported since 2016.
Via, a PRNT assay, we discovered 25.8% of peoplemissing YF-neutralizing antibodies. Moreover, neutralizing antibodies weren’t detected in 10 people with confirmed vaccination. Our findings reinforce the significance of surveillance methods and the necessity of an pressing intensification of immunization packages in areas with YFV circulation.
Monitoring vulnerable people that might act as potential disseminators for YFV in danger areas also needs to be thought of.
genediag
Human NT-3 |
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| MBS691786-5x001mg | MyBiosource | 5x0.01mg | EUR 1725 |
human anti-human NT-proBNP mAb(A1) |
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| E4A09G05-A1 | EnoGene | 50ug | EUR 275 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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human anti-human NT-proBNP mAb(B2) |
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| E4A09G05-B2 | EnoGene | 50ug | EUR 275 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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human anti-human NT-proBNP mAb(C3) |
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| E4A09G05-C3 | EnoGene | 50ug | EUR 275 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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Human Human NT-3 Protein |
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| PRP1044-10g | Abbkine | 10 µg | EUR 79 |
Human Human NT-3 Protein |
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| PRP1044-500g | Abbkine | 500 µg | EUR 1669 |
Human Human NT-3 Protein |
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| PRP1044-50g | Abbkine | 50 µg | EUR 289 |
Mouse Monoclonal anti-human NT-3 |
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| hAP-0496 | Angio Proteomie | 100ug | EUR 250 |
Sheep Polyclonal anti-human NT-3 |
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| hAP-5366 | Angio Proteomie | 50ug | EUR 400 |
NT-3, human recombinant |
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| 4306-10 | Biovision | each | EUR 320.4 |
NT-3, human recombinant |
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| 4306-1000 | Biovision | each | EUR 6434.4 |
NT-3, human recombinant |
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| 4306-50 | Biovision | each | EUR 874.8 |
Recombinant Human NT-3 |
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| EPT238 | ELK Biotech | 50ug | EUR 491.4 |
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Description: Recombinant Human Neurotrophin-3 is produced by our E.coli expression system and the target gene encoding Tyr139-Thr257 is expressed. |
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Anti-NT-3 antibody |
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| STJ98718 | St John's Laboratory | 200 µl | EUR 236.4 |
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Description: NT-3 is a protein encoded by the NTF3 gene which is approximately 29,4 kDa. NT-3 is secreted and is involved in apoptotic pathways in synovial fibroblasts, the GPCR pathway, ERK signalling, TGF-beta pathway and nanog in mammalian ESC pluripotency. This protein falls under the neurotrophin family. It controls survival and differentiation of mammalian neurons and is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo. NT-3 is expressed in the brain and peripheral tissues. Mutations in the NTF3 gene result in diabetic neuropathy and pediatric fibrosarcoma. STJ98718 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This polyclonal antibody binds to endogenous NT-3. |
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Mouse Monoclonal anti-human Neurotrophin-3 (NT-3) |
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| hAP-0235 | Angio Proteomie | 100ug | EUR 250 |
Sheep Polyclonal anti-Human Neurotrophin-3 (NT-3) |
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| hAP-5834 | Angio Proteomie | 50ug | EUR 400 |
Human Neurotrophin 3(NT-3) Elisa |
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| EK711241 | AFG Bioscience LLC | 96 Wells | EUR 0.15 |
Human 3-NT ELISA Kit |
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| EHA0677 | Abclonal | 96Tests | EUR 625.2 |
Human NT-3 ELISA Kit |
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| EHN0025 | Abclonal | 96Tests | EUR 625.2 |
Human NT-3 ELISA KIT |
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| EF000198 | Nova Lifetech | 96tests | EUR 566 |
Human NT-3 ELISA kit |
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| LF-EK50297 | Abfrontier | 1×96T | EUR 777.6 |
NT-3 Human ELISA Kit |
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| MBS355420-5x96Tests | MyBiosource | 5x96Tests | EUR 2190 |
NT-3 Human ELISA Kit |
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| MBS355420-96Tests | MyBiosource | 96Tests | EUR 485 |
SUMO-2/3 (human) (NT) polyclonal antibody |
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| MBS565241-0025mL | MyBiosource | 0.025mL | EUR 250 |
SUMO-2/3 (human) (NT) polyclonal antibody |
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| MBS565241-01mL | MyBiosource | 0.1mL | EUR 590 |
SUMO-2/3 (human) (NT) polyclonal antibody |
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| MBS565241-5x01mL | MyBiosource | 5x0.1mL | EUR 2495 |
Human NT-3 Recombinant Protein |
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| 100-086 | ReliaTech | 10 µg | EUR 196.35 |
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Description: NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues). Human and Mouse NT-3 sequences are identical |
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Human NT-3 Recombinant Protein |
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| 100-086S | ReliaTech | 2 µg | EUR 92.4 |
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Description: NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues). Human and Mouse NT-3 sequences are identical |
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Recombinant Human NT-3 Protein |
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| PROTP20783-1 | BosterBio | 10ug | EUR 380.4 |
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Description: NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues). Human and Mouse NT-3 sequences are identical. |
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Human Neurotrophin3,NT-3 ELISA |
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| SL1267Hu | Sunlong | 96 Tests | EUR 468 |
Anti-NT-3 NTF3 Antibody |
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| A03348-1 | BosterBio | 100ul | EUR 380 |
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Description: Boster Bio Anti-NT-3 NTF3 Antibody catalog # A03348-1. Tested in ELISA, Flow Cytometry, IHC applications. This antibody reacts with Human, Mouse, Rat. |
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Human Neurotrophin-3 (NT-3) CLIA Kit |
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| abx196112-96tests | Abbexa | 96 tests | EUR 990 |
Human NT-3 (Neurotrophin 3) ELISA Kit |
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| EKE61096-5x96T | Biomatik Corporation | 5x96T | EUR 3124.08 |
Human NT-3 (Neurotrophin 3) ELISA Kit |
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| EKE61096-96T | Biomatik Corporation | 96T | EUR 657.7 |
Human NT-3(Neurotrophin 3) ELISA Kit |
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| RE3096H-48wells | Reed Biotech | 48 wells | EUR 116.55 |
Human NT-3(Neurotrophin 3) ELISA Kit |
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| RE3096H-96wells | Reed Biotech | 96 wells | EUR 161.55 |
Human NT-3 -Neurotrophin-3- CLIA Kit |
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| E-CL-H1171-24Tests | Elabscience Biotech | 24 Tests | EUR 180 |
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Description: Sandwich |
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Human NT-3 -Neurotrophin-3- CLIA Kit |
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| E-CL-H1171-48Tests | Elabscience Biotech | 48 Tests | EUR 546 |
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Description: Sandwich |
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Human NT-3 -Neurotrophin-3- CLIA Kit |
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| E-CL-H1171-96Tests | Elabscience Biotech | 96 Tests | EUR 682 |
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Description: Sandwich |
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Human NT-3 -Neurotrophin-3- CLIA Kit |
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| E-CL-H1171-96Tests10 | Elabscience Biotech | 96 Tests *10 | EUR 6820 |
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Description: Sandwich |
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Human NT-3 -Neurotrophin-3- CLIA Kit |
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| E-CL-H1171-96Tests5 | Elabscience Biotech | 96 Tests *5 | EUR 3410 |
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Description: Sandwich |
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Human NT-3 (Neurotrophin-3) CLIA Kit |
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| MBS2531545-5x96Tests | MyBiosource | 5x96Tests | EUR 2565 |
Human NT-3 (Neurotrophin-3) CLIA Kit |
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| MBS2531545-96Tests | MyBiosource | 96Tests | EUR 560 |
Human Neurotrophin 3 (NT-3) ELISA Kit |
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| MBS3801248-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human Neurotrophin 3 (NT-3) ELISA Kit |
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| MBS3801248-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human Neurotrophin 3 (NT-3) ELISA Kit |
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| MBS3801248-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human Neurotrophin 3 (NT-3) ELISA Kit |
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| MBS3801248-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Human NT-3(Neurotrophin 3) ELISA Kit |
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| RE3096H-48wellsplate | Reed Biotech | 48 wells plate | EUR 126 |
Human NT-3(Neurotrophin 3) ELISA Kit |
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| RE3096H-96wellsplate | Reed Biotech | 96 wells plate | EUR 180 |
Human NT-3(Neurotrophin 3) ELISA Kit |
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| SYP-H0422-48wellsplate | UpingBio | 48 wells plate | EUR 180 |
Human NT-3(Neurotrophin 3) ELISA Kit |
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| SYP-H0422-96wellsplate | UpingBio | 96 wells plate | EUR 220 |
Human NT-3(Neurotrophin-3) ELISA Kit |
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| EH0245 | FN Test | 96T | EUR 628.92 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
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Human NT-3(Neurotrophin-3) ELISA Kit |
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| EKF58521-48T | Biomatik Corporation | 48T | EUR 396.9 |
Human NT-3(Neurotrophin-3) ELISA Kit |
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| EKF58521-5x96T | Biomatik Corporation | 5x96T | EUR 2693.25 |
Human NT-3(Neurotrophin-3) ELISA Kit |
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| EKF58521-96T | Biomatik Corporation | 96T | EUR 567 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| EKC34811-48T | Biomatik Corporation | 48T | EUR 389.34 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| EKC34811-5x96T | Biomatik Corporation | 5x96T | EUR 2641.95 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| EKC34811-96T | Biomatik Corporation | 96T | EUR 556.2 |
Human Neurotrophin-3(NT-3) Elisa Kit |
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| EK713202 | AFG Bioscience LLC | 96 Wells | EUR 0.33 |
Human NT-3(Neurotrophin-3) ELISA Kit |
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| E39EH0245 | EnoGene | 96T | EUR 595 |
Human Neurotrophin-3, NT-3 ELISA KIT |
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| CSB-E04686h-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Quantitativesandwich ELISA kit for measuring Human Neurotrophin-3, NT-3 in samples from serum, plasma, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Human Neurotrophin-3, NT-3 ELISA KIT |
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| 1-CSB-E04686h | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Human Neurotrophin-3, NT-3 in samples from serum, plasma, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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Human Neurotrophin-3,NT-3 ELISA KIT |
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| CN-03259H1 | ChemNorm | 96T | EUR 525.6 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| CN-03259H2 | ChemNorm | 48T | EUR 346.8 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| YLA1770HU-48T | Shanghai YL Biotech | 48T | Ask for price |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| YLA1770HU-96T | Shanghai YL Biotech | 96T | Ask for price |
Human Neurotrophin-3(NT-3)ELISA Kit |
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| GA-E1322HM-48Tests | GenAsia Biotech | 48 Tests | Ask for price |
Human Neurotrophin-3(NT-3)ELISA Kit |
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| GA-E1322HM-96Tests | GenAsia Biotech | 96 Tests | EUR 388 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| E1305Hu-1096T | Jiaxing Korain Biotech Ltd (BT Labs) | 10*96T | EUR 4122 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| E1305Hu-48wells | Jiaxing Korain Biotech Ltd (BT Labs) | 48 wells | EUR 300 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| E1305Hu-596T | Jiaxing Korain Biotech Ltd (BT Labs) | 5*96T | EUR 2061 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| E1305Hu-96wells | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| E5769Hu-1096T | Jiaxing Korain Biotech Ltd (BT Labs) | 10*96T | EUR 4122 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| E5769Hu-48wells | Jiaxing Korain Biotech Ltd (BT Labs) | 48 wells | EUR 300 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| E5769Hu-596T | Jiaxing Korain Biotech Ltd (BT Labs) | 5*96T | EUR 2061 |
Human Neurotrophin-3,NT-3 ELISA KIT |
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| E5769Hu-96wells | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Human Neurotrophin-3(NT-3)ELISA Kit |
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| GA-E1322HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
Human Neurotrophin-3(NT-3)ELISA Kit |
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| GA-E1322HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
Human Neurotrophin-3(NT-3)ELISA Kit |
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| QY-E01634 | Qayee Biotechnology | 96T | EUR 433.2 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS704206-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 4585 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS704206-24StripWellsLIMIT1 | MyBiosource | 24-Strip-Wells(LIMIT1) | EUR 275 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS704206-48StripWells | MyBiosource | 48-Strip-Wells | EUR 395 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS704206-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2405 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS704206-96StripWells | MyBiosource | 96-Strip-Wells | EUR 555 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS161637-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3460 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS161637-48StripWells | MyBiosource | 48-Strip-Wells | EUR 285 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS161637-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1750 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS161637-96StripWells | MyBiosource | 96-Strip-Wells | EUR 425 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS1606656-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3460 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS1606656-48StripWells | MyBiosource | 48-Strip-Wells | EUR 285 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS1606656-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1750 |
Human Neurotrophin-3, NT-3 ELISA Kit |
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| MBS1606656-96StripWells | MyBiosource | 96-Strip-Wells | EUR 425 |
Human NT-3 (Neurotrophin-3) ELISA Kit |
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| MBS2507932-10x96Tests | MyBiosource | 10x96Tests | EUR 4060 |
Human NT-3 (Neurotrophin-3) ELISA Kit |
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| MBS2507932-24Tests | MyBiosource | 24Tests | EUR 265 |
Human NT-3 (Neurotrophin-3) ELISA Kit |
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| MBS2507932-48Tests | MyBiosource | 48Tests | EUR 450 |
Human NT-3 (Neurotrophin-3) ELISA Kit |
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| MBS2507932-5x96Tests | MyBiosource | 5x96Tests | EUR 2265 |
Human NT-3 (Neurotrophin-3) ELISA Kit |
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| MBS2507932-96Tests | MyBiosource | 96Tests | EUR 535 |
Molecular and structural foundation for Lewis glycan recognition by a cancer-targeting antibody
Immunotherapy has been profitable in treating many tumour sorts. The event of extra tumour-antigen binding monoclonal antibodies (mAbs) will assist develop the vary of immunotherapeutic targets. Lewis histo-blood group and associated glycans are overexpressed on many carcinomas, together with these of the colon, lung, breast, prostate and ovary, and might due to this fact be selectively focused by mAbs.
- Right here we look at the molecular and structural foundation for recognition of prolonged Lea and Lexcontaining glycans by a chimeric mAb. Each the murine (FG88.2) IgG3 and a chimeric (ch88.2) IgG1 mAb variants confirmed reactivity to colorectal most cancers cells resulting in considerably decreased cell viability.
- We decided the X-ray construction of the unliganded ch88.2 fragment antigen-binding (Fab) containing two Fabs within the unit cell. A mix of molecular docking, glycan grafting and molecular dynamics simulations predicts two distinct subsites for recognition of Lea and Lex trisaccharides.
- Whereas gentle chain residues have been completely used for Lea binding, recognition of Lex concerned each gentle and heavy chain residues. An prolonged groove is predicted to accommodate the Lea-Lex hexasaccharide with adjoining subsites for every trisaccharide.
- The molecular and structural particulars of the ch88.2 mAb offered right here present perception into its cross-reactivity for varied Lea and Lexcontaining glycans. Moreover, the anticipated interactions with prolonged epitopes seemingly explains the selectivity of this antibody for concentrating on Lewis-positive tumours.
Dynamic modifications of throat swabs RNA and serum antibodies for SARS-CoV-2 and their diagnostic performances in sufferers with COVID-19
Dynamic modifications of RNA and antibodies in SARS-CoV-2 contaminated sufferers stay largely unknown, and affect components for antibody manufacturing haven’t been totally clarified. On this research, we enrolled 475 circumstances of COVID-19 and 389 controls. Consecutive throat swabs specimens (n=1875) from 187 sufferers have been collected to analyzed the dynamic modifications of RNA. Furthermore, 162 serial serum samples from 31 sufferers have been examined for seroconversion of IgM and IgG.
In the meantime, IgM and IgG have been additionally detected in 409 COVID-19 sufferers and 389 controls. Moreover, the logistic regression evaluation was executed to establish the attainable affect components for antibody manufacturing. The median constructive conversion time for RNA was day 7 (IQR, 3-11), and the constructive price was the very best within the early stage (74.59 % at day 1-5) after which regularly decreased. The median time of seroconversion for IgM and IgG have been each day 12 (IQR, 10-15).
The sensitivity and specificity for IgM (or IgG) was 87.04 % and 96.92 %, respectively. The constructive charges of IgM and IgG have been each low on the day 1-5 (18.52% for IgM, 14.81% for IgG), after which considerably elevated. Multivariate logistic regression indicated that decreased lymphocytes and quick constructive conversion time for SARS-CoV-2 RNA have been unbiased components for unfavourable outcomes of IgM and IgG assessments. In conclusion, dynamic modifications of RNA, IgM and IgG in opposition to SARS-CoV-2, particularly antibodies, have been distinctive and they need to be mixed for COVID-19 analysis. And antibodies seroconversion was influenced by the decreased lymphocytes and quick constructive conversion time for RNA.
human anti-human IL-4 mAb (52) |
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| E4A09D04-52 | EnoGene | 50ug | EUR 255 |
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Description: Available in various conjugation types. |
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human anti-human IL-4 mAb (C1) |
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| E4A09D04-C1 | EnoGene | 50ug | EUR 255 |
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Description: Available in various conjugation types. |
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Rat Anti Human Interleukin-4, IL-4, unconjugated |
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| MBS396740-01mg | MyBiosource | 0.1mg | EUR 260 |
Rat Anti Human Interleukin-4, IL-4, unconjugated |
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| MBS396740-5x01mg | MyBiosource | 5x0.1mg | EUR 1015 |
Rat Anti Human Interleukin-4, IL-4, unconjugated |
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| MBS396742-01mg | MyBiosource | 0.1mg | EUR 260 |
Rat Anti Human Interleukin-4, IL-4, unconjugated |
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| MBS396742-5x01mg | MyBiosource | 5x0.1mg | EUR 1015 |
Rat Anti Human Interleukin-4, IL-4, unconjugated |
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| MBS396744-01mg | MyBiosource | 0.1mg | EUR 260 |
Rat Anti Human Interleukin-4, IL-4, unconjugated |
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| MBS396744-5x01mg | MyBiosource | 5x0.1mg | EUR 1015 |
Anti-Human IL-4 |
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| GWB-BIG229 | GenWay Biotech | 500ug | Ask for price |
Anti-Human IL-4 |
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| MBS550674-01mg | MyBiosource | 0.1mg | EUR 260 |
Anti-Human IL-4 |
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| MBS550674-02mg | MyBiosource | 0.2mg | EUR 335 |
Anti-Human IL-4 |
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| MBS550686-01mg | MyBiosource | 0.1mg | EUR 260 |
Anti-Human IL-4 |
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| MBS550686-02mg | MyBiosource | 0.2mg | EUR 335 |
Anti‐Human IL‐17A |
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| E2790213 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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IL-4， Human |
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| E34M006H | EnoGene | 5 μg | EUR 155 |
Human IL-4 |
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| GWB-CB2917 | GenWay Biotech | 0.01 mg | Ask for price |
Human IL-4 |
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| gAP-0227 | Angio Proteomie | 1mg | EUR 450 |
Human IL-4 |
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| MBS691496-0002mg | MyBiosource | 0.002mg | EUR 225 |
Human IL-4 |
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| MBS691496-5x0002mg | MyBiosource | 5x0.002mg | EUR 725 |
Human IL-4 |
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| MBS691811-005mg | MyBiosource | 0.05mg | EUR 555 |
Human IL-4 |
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| MBS691811-5x005mg | MyBiosource | 5x0.05mg | EUR 2205 |
Human IL-4 |
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| MBS691915-001mg | MyBiosource | 0.01mg | EUR 265 |
Human IL-4 |
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| MBS691915-5x001mg | MyBiosource | 5x0.01mg | EUR 890 |
IL-4, Human |
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| MBS8575163-0005mg | MyBiosource | 0.005mg | EUR 245 |
IL-4, Human |
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| MBS8575163-5x0005mg | MyBiosource | 5x0.005mg | EUR 940 |
Anti-Human IL-4 Antibody |
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| 101-M05 | ReliaTech | 500 µg | EUR 246.75 |
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Description: Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities. |
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Anti-Human IL-4 Antibody |
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| 101-M508 | ReliaTech | 100 µg | EUR 399 |
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Description: Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities. |
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Anti-Human IL-4 Antibody |
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| 102-P34 | ReliaTech | 100 µg | EUR 245.7 |
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Description: Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities. |
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Anti-human IL-4 antibody |
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| STJ15100045 | St John's Laboratory | 250 µg | EUR 403.2 |
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Description: This monoclonal antibody enables sensitive and specific detection of human IL-4 in immunoassays such as ELISA and ELISpot. |
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Anti-human IL-4 antibody |
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| STJ15100046 | St John's Laboratory | 250 µg | EUR 440.4 |
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Description: This monoclonal antibody enables sensitive and specific detection of human IL-4 in immunoassays such as ELISA and ELISpot. |
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Human Interleukin-4 (IL-4) Antibody |
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| 32184-05111 | AssayPro | 150 ug | EUR 215 |
Anti-Human IL-4 PE |
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| MBS697227-100Tests | MyBiosource | 100Tests | EUR 360 |
Anti-Human IL-4 PE |
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| MBS697227-25Tests | MyBiosource | 25Tests | EUR 215 |
Anti-Human IL-4 PE |
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| MBS697227-5x100Tests | MyBiosource | 5x100Tests | EUR 1580 |
Anti-Human IL-4 PE |
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| MBS697234-100Tests | MyBiosource | 100Tests | EUR 335 |
Anti-Human IL-4 PE |
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| MBS697234-25Tests | MyBiosource | 25Tests | EUR 185 |
Anti-Human IL-4 PE |
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| MBS697234-5x100Tests | MyBiosource | 5x100Tests | EUR 1475 |
Anti-Human IL-4 APC |
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| MBS697235-100Tests | MyBiosource | 100Tests | EUR 320 |
Anti-Human IL-4 APC |
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| MBS697235-25Tests | MyBiosource | 25Tests | EUR 185 |
Anti-Human IL-4 APC |
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| MBS697235-5x100Tests | MyBiosource | 5x100Tests | EUR 1395 |
Mouse Anti-Human IL-4 |
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| MBS690917-05mg | MyBiosource | 0.5mg | EUR 525 |
Mouse Anti-Human IL-4 |
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| MBS690917-5x05mg | MyBiosource | 5x0.5mg | EUR 2080 |
Human Interleukin-4 (IL-4) |
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| 1-CSB-EP011659HU | Cusabio |
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Description: Recombinant Human Interleukin-4(IL-4) expressed in E.coli |
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Interleukin-4 (IL-4) Human |
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| GWB-2A39E4 | GenWay Biotech | 0.01 mg | Ask for price |
IL-4, Interleukin-4, human |
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| RC212-15 | Bio Basic | 5ug | EUR 125.26 |
human anti-human IL-2 mAb |
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| E409C12-h100 | EnoGene | 100μL | EUR 395 |
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Description: Available in various conjugation types. |
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human anti-human IL-5 mAb |
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| E409C14-h100 | EnoGene | 100μL | EUR 395 |
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Description: Available in various conjugation types. |
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human anti-human IL-8 mAb |
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| E409C16-h100 | EnoGene | 100μL | EUR 395 |
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Description: Available in various conjugation types. |
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human anti-human IL-5 mAb |
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| E4A09D05 | EnoGene | 50ug | EUR 255 |
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Description: Available in various conjugation types. |
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Human anti-Human IL-2 mAb |
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| MBS8576800-005mg | MyBiosource | 0.05mg | EUR 325 |
Human anti-Human IL-2 mAb |
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| MBS8576800-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
Human anti-Human IL-2 mAb |
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| MBS8576800-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
Human anti-Human IL-2 mAb |
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| MBS8576800-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
Human anti-Human IL-2 mAb |
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| MBS8576800-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
Human anti-Human IL-5 mAb |
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| MBS8576804-005mg | MyBiosource | 0.05mg | EUR 325 |
Human anti-Human IL-5 mAb |
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| MBS8576804-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
Human anti-Human IL-5 mAb |
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| MBS8576804-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
Human anti-Human IL-5 mAb |
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| MBS8576804-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
Human anti-Human IL-5 mAb |
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| MBS8576804-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
Human anti-Human IL-8 mAb |
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| MBS8576808-005mg | MyBiosource | 0.05mg | EUR 325 |
Human anti-Human IL-8 mAb |
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| MBS8576808-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
Human anti-Human IL-8 mAb |
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| MBS8576808-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
Human anti-Human IL-8 mAb |
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| MBS8576808-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
Human anti-Human IL-8 mAb |
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| MBS8576808-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
human anti-human IL-1β mAb |
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| E409C11-h100 | EnoGene | 100μL | EUR 395 |
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Description: Available in various conjugation types. |
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human anti-human IL-10 mAb |
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| E409C17-h100 | EnoGene | 100μL | EUR 395 |
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Description: Available in various conjugation types. |
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Human anti-Human IL-10 mAb |
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| MBS8576810-005mg | MyBiosource | 0.05mg | EUR 325 |
Human anti-Human IL-10 mAb |
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| MBS8576810-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
Human anti-Human IL-10 mAb |
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| MBS8576810-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
Human anti-Human IL-10 mAb |
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| MBS8576810-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
Human anti-Human IL-10 mAb |
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| MBS8576810-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
Human anti-Human IL-1beta mAb |
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| MBS8576798-005mg | MyBiosource | 0.05mg | EUR 325 |
Human anti-Human IL-1beta mAb |
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| MBS8576798-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
Human anti-Human IL-1beta mAb |
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| MBS8576798-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
Human anti-Human IL-1beta mAb |
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| MBS8576798-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
Human anti-Human IL-1beta mAb |
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| MBS8576798-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
rec IL-4 (human) |
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| H-9630.0002 | Bachem | 2.0µg | EUR 313.2 |
rec IL-4 (human) |
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| H-9630.0010 | Bachem | 10.0µg | EUR 1140 |
human anti-human IL-12/IL-23 p40 mAb(3H2) |
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| E4A09D33-3H2 | EnoGene | 50ug | EUR 275 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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human anti-human IL-12/IL-23 p40 mAb(5N9) |
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| E4A09D33-5N9 | EnoGene | 50ug | EUR 275 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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PE Anti-Human IL-4 Antibody |
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| DL22181F-20Tests | DL Develop | 20Tests | EUR 222.5 |
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Description: IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells. |
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