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August 24, 2020

Antibody-Protein binding and Conformational changes

By Karina

A high-throughput neutralizing antibody assay for COVID-19 analysis and vaccine analysis

 

Virus neutralization stays the gold normal for figuring out antibody efficacy. Due to this fact, a high-throughput assay to measure SARS-CoV-2 neutralizing antibodies is urgently wanted for COVID-19 serodiagnosis, convalescent plasma remedy, and vaccine growth.
Right here, we report on a fluorescence-based SARS-CoV-2 neutralization assay that detects SARS-CoV-2 neutralizing antibodies in COVID-19 affected person specimens and yields comparable outcomes to plaque discount neutralizing assay, the gold normal of serological testing.
The fluorescence-based neutralization assay is restricted to measure COVID-19 neutralizing antibodies with out cross reacting with affected person specimens with different viral, bacterial, or parasitic infections. Collectively, our method affords a fast platform that may be scaled to display folks for antibody safety from COVID-19, a key parameter essential to soundly reopen native communities.

Antibody-protein binding and conformational modifications: figuring out allosteric signalling pathways to engineer a greater effector response

Quite a few monoclonal antibodies have been developed efficiently for the therapy of varied ailments. Nonetheless, the event of biotherapeutic antibodies is advanced, costly, and time-consuming, and to facilitate this course of, cautious structural evaluation past the antibody binding web site is required to develop a extra efficacious antibody.
  • On this work, we targeted on protein antigens, since they induce the most important antibody modifications, and supply attention-grabbing instances to match and distinction. The constructions of 15 anti-protein antibodies had been analysed to match the antigen-bound/unbound types.
  • Surprisingly, three completely different courses of binding-induced modifications had been recognized. In school (B1), the antigen binding fragment distorted considerably, and we discovered modifications within the loop area of the heavy chain’s fixed area; this corresponds properly with anticipated allosteric actions. In school (B2), we discovered modifications in the identical loop area with out the general distortion.
  • In school (B3), these modifications didn’t current, and solely native modifications on the complementarity figuring out areas had been discovered. Consequently, structural evaluation of antibodies is essential for therapeutic growth. Cautious analysis of allosteric actions should be undertaken
  • to develop higher effector responses, particularly in the course of the transformation of those antibodies from small fragments on the discovery stage to full antibodies on the subsequent growth phases.
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IL-17, Interleukin-17 IL-17A, human
RC212-28 5ug
EUR 104.38
  • Product category: Proteins/Recombinant Proteins/Cytokines

IL-17, Human
HY-P7036 10ug
EUR 211

IL-17
E5-00007 1mg
EUR 960

IL-17
EF014060 96 Tests
EUR 689

IL-17
MO15110 500 ug
EUR 910

IL-17
PR27113 5 ug
EUR 191

Anti-IL-17 alpha antibody
STJ93683 200 µl
EUR 197
Description: Rabbit polyclonal to IL-17Ralpha.

IL-17/IL-17A
E21-021 10ug
EUR 343

IL-6, Interleukin-6, rat
RC252-17 2ug
EUR 104.38
  • Product category: Proteins/Recombinant Proteins/Cytokines

Recombinant Human IL-17
SJB09-03 25µg/vial
EUR 256

IL-6, Interleukin-6, murine (mouse)
RC232-17 2ug
EUR 104.38
  • Product category: Proteins/Recombinant Proteins/Cytokines

Interleukin 17 (IL-17) Antibody
abx234224-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Interleukin 17 (IL-17) Antibody
abx234225-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Bovine Interleukin 17(IL-17)
QY-E60069 96T
EUR 426

IL-6, Interleukin-6, monkey (rhesus macaque)
RC222-17 2ug
EUR 104.38
  • Product category: Proteins/Recombinant Proteins/Cytokines

IL-17 Antibody
24784-100ul 100ul
EUR 390

IL-17 Antibody
24789-100ul 100ul
EUR 390

IL-17 Antibody
5176-100
EUR 338

Human Interleukin 17,IL-17 ELISA Kit
201-12-0143 96 tests
EUR 440
  • This Interleukin 17 ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Interleukin 17 (IL-17) CLIA Kit
abx195860-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Human Interleukin 17,IL-17 ELISA Kit
CN-03335H1 96T
EUR 434

Human Interleukin 17,IL-17 ELISA Kit
CN-03335H2 48T
EUR 284

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-48T 48T
EUR 289

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-96T 96T
EUR 466

IL-17 Interleukin-17 Human Recombinant Protein
PROTQ16552-1 Regular: 25ug
EUR 317
Description: Interleukin-17A Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids (2 chains of 132 aa) and having a molecular mass of 31kDa.  ;The IL-17 is purified by proprietary chromatographic techniques.

Human Interleukin 17(IL-17)ELISA Kit
QY-E04323 96T
EUR 361

Recombinant Human IL-17 (IL-17A) Protein
PROTQ16552-4 25ug
EUR 317
Description: The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules.  Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles.  The six known members of this family, IL-17A through IL-17F, are secreted as homodimers.  IL-17A exhibits cross-species bioactivity between human and murine cells.  Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains.

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 349

human IL-17, His tag
E410A10-100 100μg
EUR 960

IL-17 (Human) ELISA Kit
E4628-100
EUR 729

IL-17 ELISA KIT|Human
EF006939 96 Tests
EUR 689

Human IL-17 ELISA kit
LF-EK50201 1×96T
EUR 648

Human Interleukin 17 (IL-17) Detection Assay Kit
6808 1 kit
EUR 483.55
Description: Human Interleukin 17 (IL-17) Detection Assay Kit

ELISA kit for Human IL-17 (Interleukin 17)
E-EL-H0105 1 plate of 96 wells
EUR 377
  • Gentaur's IL-17 ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human IL-17. Standards or samples are added to the micro ELISA plate wells and combined with
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Human IL-17 (Interleukin 17) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Human IL-17 (Interleukin 17)
E-CL-H0104 1 plate of 96 wells
EUR 584
  • Gentaur's IL-17 CLIA kit utilizes the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human IL-17 . Standards or samples are added to the micro CLIA plate wells and combined with th
  • Show more
Description: A sandwich CLIA kit for quantitative measurement of Human IL-17 (Interleukin 17) in samples from Serum, Plasma, Cell supernatant

IL-17 Interleukin-17 Human Recombinant Protein, HEK
PROTQ16552 Regular: 10ug
EUR 317
Description: IL-17 Human Recombinant produced in HEK cells is a glycosylated homodimer, having a molecular weight range of 30-35kDa due to glycosylation.;The IL-17 is purified by proprietary chromatographic techniques.

17-Hydroxyprogesterone (17-OHP) ELISA Kit
DLR-17-OHP-Ge-48T 48T
EUR 469
  • Should the 17-Hydroxyprogesterone (17-OHP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of 17-Hydroxyprogesterone (17-OHP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

17-Hydroxyprogesterone (17-OHP) ELISA Kit
DLR-17-OHP-Ge-96T 96T
EUR 608
  • Should the 17-Hydroxyprogesterone (17-OHP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of 17-Hydroxyprogesterone (17-OHP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Polyclonal IL-17 Antibody
APR06508G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IL-17 . This antibody is tested and proven to work in the following applications:

Polyclonal IL-17 Antibody
APR06512G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IL-17 . This antibody is tested and proven to work in the following applications:

rHu IL-17-A
AK8249-0005 5µg Ask for price

rHu IL-17-A
AK8249-0025 25µg Ask for price

rHu IL-17-A
AK8249-0100 100µg Ask for price

rHu IL-17-A
AK8249-1000 1mg Ask for price

rHu IL-17-E
AK8299-0005 5µg Ask for price

rHu IL-17-E
AK8299-0025 25µg Ask for price

rHu IL-17-E
AK8299-0100 100µg Ask for price

rHu IL-17-E
AK8299-1000 1mg Ask for price

rHu IL-17-F
AK8312-0005 5µg Ask for price

rHu IL-17-F
AK8312-0025 25µg Ask for price

rHu IL-17-F
AK8312-0100 100µg Ask for price

rHu IL-17-F
AK8312-1000 1mg Ask for price

General 17-Hydroxyprogesterone (17-OHP) ELISA Kit
RD-17-OHP-Ge-48Tests 48 Tests
EUR 467

General 17-Hydroxyprogesterone (17-OHP) ELISA Kit
RD-17-OHP-Ge-96Tests 96 Tests
EUR 646

General 17-Hydroxyprogesterone (17-OHP) ELISA Kit
RDR-17-OHP-Ge-48Tests 48 Tests
EUR 488

General 17-Hydroxyprogesterone (17-OHP) ELISA Kit
RDR-17-OHP-Ge-96Tests 96 Tests
EUR 676

Chicken Interleukin 17, IL-17 ELISA Kit
CSB-E04607Ch-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Chicken Interleukin 17, IL-17 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Chicken Interleukin 17, IL-17 ELISA Kit
1-CSB-E04607Ch
  • EUR 603.00
  • EUR 4247.00
  • EUR 2260.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Chicken Interleukin 17, IL-17 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Interleukin 17, IL-17 ELISA Kit
CSB-E04608m-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin 17, IL-17 in samples from serum, plasma, tissue homogenates, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Interleukin 17, IL-17 ELISA Kit
1-CSB-E04608m
  • EUR 603.00
  • EUR 4247.00
  • EUR 2260.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin 17, IL-17 in samples from serum, plasma, tissue homogenates, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Interleukin 17 (IL-17) CLIA Kit
abx195861-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Rat Interleukin 17 (IL-17) CLIA Kit
abx195862-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Chicken Interleukin-17, IL-17 ELISA Kit
ELA-E0063d 96 Tests
EUR 928

Porcine Interleukin-17, IL-17 ELISA Kit
ELA-E0063p 96 Tests
EUR 928

Rat Interleukin 17, IL- 17 ELISA Kit
ELA-E0063r 96 Tests
EUR 886

Rabbit Interleukin-17, IL-17 ELISA Kit
ELA-E0063Rb 96 Tests
EUR 928

Hamster IL-17(Interleukin 17) ELISA Kit
EHA0007 96T
EUR 567.6
  • Detection range: 31.25-2000 pg/ml
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Hamster;Sensitivity: 18.75pg/ml

Canine IL-17(Interleukin 17) ELISA Kit
ECA0032 96T
EUR 567.6
  • Detection range: 31.25-2000 pg/ml
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Canine;Sensitivity: 18.75pg/ml

Chicken IL-17(Interleukin 17) ELISA Kit
ECH0038 96T
EUR 567.6
  • Detection range: 15.625-1000 pg/ml
  • Alias: IL-17(Interleukin 17)/CTLA-8/IL17A/IL-17CTLA-8/IL17interleukin-17A/interleukin 17A
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Chicken;Sensitivity: 9.375pg/ml

Rabbit Interleukin 17,IL-17 ELISA Kit
CN-00640R1 96T
EUR 452

Rabbit Interleukin 17,IL-17 ELISA Kit
CN-00640R2 48T
EUR 302

Chicken Interleukin 17,IL-17 ELISA Kit
CN-00838C1 96T
EUR 452

Chicken Interleukin 17,IL-17 ELISA Kit
CN-00838C2 48T
EUR 302

PoFAine interleukin 17,IL-17 ELISA Kit
CN-01210P2 48T
EUR 326

PoFAine interleukin 17,IL-17 ELISA Kit
CN-01211P1 96T
EUR 449

PoFAine interleukin 17,IL-17 ELISA Kit
CN-01211P2 48T
EUR 299

Rat Interleukin 17, IL-17 ELISA KIT
CSB-E07451r-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat Interleukin 17, IL-17 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Interleukin 17, IL-17 ELISA KIT
1-CSB-E07451r
  • EUR 603.00
  • EUR 4247.00
  • EUR 2260.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat Interleukin 17, IL-17 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Pig interleukin 17, IL-17 ELISA Kit
CSB-E08057p-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Pig interleukin 17, IL-17 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Pig interleukin 17, IL-17 ELISA Kit
1-CSB-E08057p
  • EUR 603.00
  • EUR 4247.00
  • EUR 2260.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Pig interleukin 17, IL-17 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit Interleukin 17, IL-17 ELISA Kit
CSB-E08058Rb-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rabbit Interleukin 17, IL-17 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rabbit Interleukin 17, IL-17 ELISA Kit
1-CSB-E08058Rb
  • EUR 603.00
  • EUR 4247.00
  • EUR 2260.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rabbit Interleukin 17, IL-17 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Bovine Interleukin 17(IL-17) ELISA Kit
CSB-E14207B-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Bovine Interleukin 17 (IL-17) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Bovine Interleukin 17(IL-17) ELISA Kit
1-CSB-E14207B
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Bovine Interleukin 17(IL-17) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Canine Interleukin 17(IL-17)ELISA Kit
CSB-E17935c-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Canine Interleukin 17 (IL-17) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Canine Interleukin 17(IL-17)ELISA Kit
1-CSB-E17935c
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Canine Interleukin 17(IL-17) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

 

Drug Tolerant Anti-drug Antibody Assay for Infliximab Remedy in Scientific Observe Identifies Constructive Instances Earlier

A subgroup of sufferers handled with infliximab lose response to the therapy and one purpose for that is the event of anti-drug antibodies (ADA). If used optimally, measuring drug and ADA degree might result in a extra personalised and environment friendly therapy regime, and allow identification of ADA-positive sufferers earlier than the underlying illness flares or allergic reactions happen.
With the usage of a drug-tolerant ADA assay which might detect ADA no matter drug ranges within the pattern, we decided the affect of ADA on therapy failure to infliximab. The goals of this research had been to estimate the real-life optimum serum infliximab (sIFX) degree and set a medical threshold worth for a drug-tolerant ADA assay. Trough ranges of sIFX had been measured with ELISA. Free ADA was measured with two drug-sensitive strategies (ELISA and a bioassay) and one drug-tolerant technique (PandA).
Two real-life cohorts handled with infliximab had been included; a cross-sectional cohort together with sufferers with inflammatory rheumatic ailments (n = 270) and a potential cohort of rheumatoid arthritis (RA) sufferers (n = 73) adopted for 1 yr. Regular vary of sIFX was estimated from the potential cohort and an arbitrary optimum drug degree was set to be between 1 and 6 μg/mL.
Utilizing this vary, optimum sIFX was present in solely 60% (163/270) of the sufferers within the cross-sectional cohort. These sufferers had considerably higher therapy response than these with a drug degree below 1 μg/mL, who had an ADA frequency of 34% (19/56) utilizing the drug-tolerant technique.
Within the potential cohort, the drug-tolerant assay might determine 34% (53/155 samples) as ADA optimistic in samples with sIFX degree >0.2 μg/mL. ADA had been seldom detected in sufferers with >1 μg/mL sIFX, with three attention-grabbing exceptions. A clinically related ADA threshold was decided to be >three RECL as measured with the drug-tolerant assay.
In a real-life setting, there was a substantial variety of sufferers with suboptimal drug ranges and a proportion of those had ADA. Each too low and too excessive drug ranges correlated with worse illness, however for various causes. Including a drug-tolerant assay enabled detection of ADA earlier and no matter drug degree at time of sampling.
Alpha V Beta 5 Integrin, Peptide Aptamer, unlabeled
AP-301-U 5 mg Ask for price
Integrin alpha 5 Antibody
49269-100ul 100ul
EUR 333
Integrin alpha 5 Antibody
49269-50ul 50ul
EUR 239
Integrin alpha-5 Antibody
abx234347-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.
Anti-Integrin alpha 5 Rabbit Monoclonal Antibody
M01911 100ug/vial
EUR 397
Description: Rabbit Monoclonal Integrin alpha 5 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.
Alpha V Beta 5 Integrin, Peptide Aptamer, FITC labelled
AP-301-F 1 mg Ask for price
Human Integrin Alpha 5 (ITGa5) Protein
20-abx067272
  • EUR 662.00
  • EUR 272.00
  • EUR 2040.00
  • EUR 787.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Integrin Alpha 5 (ITGA5) Antibody
abx026655-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.
Integrin Alpha 5 (ITGA5) Antibody
abx026655-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.
Integrin Alpha 5 (ITGA5) Antibody
20-abx006811
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.
Integrin Alpha 5 (ITGa5) Antibody
20-abx179024
  • EUR 1678.00
  • EUR 773.00
  • 1 mg
  • 200 ug
  • Please enquire.
Integrin alpha 5 (CD49e) Antibody
abx216264-100ug 100 ug
EUR 439
  • Shipped within 5-10 working days.
Integrin Alpha 5 (ITGa5) Antibody
20-abx101634
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Integrin Alpha 5 (ITGa5) Antibody
20-abx101635
  • EUR 467.00
  • EUR 133.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Integrin Alpha 5 (ITGA5) Antibody
20-abx113185
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.
Integrin Alpha 5 (ITGa5) Antibody
20-abx129339
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Integrin Alpha 5 (ITGa5) Antibody
20-abx172956
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug
  • Please enquire.
Integrin Alpha 5 (ITGA5) Antibody
abx011678-100ul 100 ul
EUR 411
  • Shipped within 5-10 working days.
Integrin alpha 5 Conjugated Antibody
C49269 100ul
EUR 397
Integrin alpha 5 (CD49e) Antibody
AF5200 200ul
EUR 304
Description: Integrin α5 (CD49e) Antibody detects endogenous levels of total Integrin α5 (CD49e).
Integrin Alpha 5 (ITGA5) Antibody
20-abx338742
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Integrin Alpha 5 (ITGA5) Antibody
20-abx327245
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.
Integrin Alpha 5 (ITGA5) Antibody
20-abx323564
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.
Integrin Alpha 5 (ITGA5) Antibody
20-abx325454
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.
Integrin alpha 5 Rabbit mAb
A19069-100ul 100 ul
EUR 410
Integrin alpha 5 Rabbit mAb
A19069-200ul 200 ul
EUR 571
Integrin alpha 5 Rabbit mAb
A19069-20ul 20 ul
EUR 221
Integrin alpha 5 Rabbit mAb
A19069-50ul 50 ul
EUR 287
Integrin Alpha 5 (ITGA5) Antibody
20-abx000873
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul
  • Shipped within 5-10 working days.
Recombinant Integrin Alpha 5 (ITGa5)
4-RPB287Bo01
  • EUR 556.96
  • EUR 252.00
  • EUR 1813.60
  • EUR 671.20
  • EUR 1242.40
  • EUR 436.00
  • EUR 4384.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q27977
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 61.6kDa
  • Isoelectric Point: 5.8
Description: Recombinant Bovine Integrin Alpha 5 expressed in: E.coli
Recombinant Integrin Alpha 5 (ITGa5)
4-RPB287Hu01
  • EUR 476.32
  • EUR 230.00
  • EUR 1511.20
  • EUR 570.40
  • EUR 1040.80
  • EUR 382.00
  • EUR 3628.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P08648
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 47.6kDa
  • Isoelectric Point: 8.4
Description: Recombinant Human Integrin Alpha 5 expressed in: E.coli
Recombinant Integrin Alpha 5 (ITGa5)
4-RPB287Mu01
  • EUR 476.32
  • EUR 230.00
  • EUR 1511.20
  • EUR 570.40
  • EUR 1040.80
  • EUR 382.00
  • EUR 3628.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P11688
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 50.0kDa
  • Isoelectric Point: 8.7
Description: Recombinant Mouse Integrin Alpha 5 expressed in: E.coli
anti-Integrin beta 5
YF-PA12792 100 ug
EUR 403
Description: Rabbit polyclonal to Integrin beta 5
anti-Integrin beta 5
YF-PA24023 50 ul
EUR 334
Description: Mouse polyclonal to Integrin beta 5
Rabbit Anti-Human Alpha Defensin 5 (NP-5),antiserum #1
HDEFA51-S 100 ul
EUR 457
Anti-Integrin alpha antibody
STJ93727 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alpha3.
Anti-Integrin alpha antibody
STJ93728 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alpha4.
Anti-Integrin alpha antibody
STJ93729 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alphaE.
Anti-Integrin alpha antibody
STJ93730 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alphaV.
Anti-Integrin alpha antibody
STJ96613 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alpha4.
Anti-Integrin alpha antibody
STJ96825 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alphaD.
Anti-Integrin alpha antibody
STJ97273 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alphaL.
Anti-Integrin alpha antibody
STJ97283 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alpha2.
Anti-Integrin alpha antibody
STJ97284 200 µl
EUR 197
Description: Integrin alpha5 is a protein encoded by the ITGA5 gene which is approximately 114,5 kDa. Integrin alpha5 is localised to the cell membrane and is involved in the MAPK-Erk pathway, apoptotic pathways, integrin pathway, focal adhesion and blood-brain barrier and immune cell transmigration. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signalling. Integrin alpha5 is expressed in the liver, lung, nervous system, bone marrow and blood. Mutations in the ITGA5 gene may result in colon carcinoma and congenital epulis STJ97284 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Integrin alpha5 protein.
Anti-Integrin alpha antibody
STJ97285 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alpha6.
Anti-Integrin alpha antibody
STJ97657 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alpha3.
Anti-Integrin alpha antibody
STJ98181 100 µl
EUR 234
Description: Mouse monoclonal to Integrin alpha5.
Anti-Integrin alpha antibody
STJ98510 100 µl
EUR 234
Description: Mouse monoclonal to Integrin alpha5.
Anti-Integrin alpha antibody
STJ98511 100 µl
EUR 234
Description: Mouse monoclonal to Integrin alpha6.
Anti-Integrin alpha antibody
STJ98709 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alpha1.
Anti-Integrin alpha antibody
STJ98737 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alphaX.
Anti-Integrin alpha antibody
STJ98984 200 µl
EUR 197
Description: Rabbit polyclonal to Integrin alphaE.
anti-Integrin alpha 6
YF-PA12761 50 ul
EUR 363
Description: Mouse polyclonal to Integrin alpha 6
anti-Integrin alpha 6
YF-PA12762 100 ug
EUR 403
Description: Rabbit polyclonal to Integrin alpha 6
anti-Integrin alpha 1
YF-PA12784 50 ug
EUR 363
Description: Mouse polyclonal to Integrin alpha 1
anti-Integrin alpha 4
YF-PA12785 100 ug
EUR 403
Description: Rabbit polyclonal to Integrin alpha 4
anti-Integrin alpha V
YF-PA12786 50 ul
EUR 363
Description: Mouse polyclonal to Integrin alpha V
anti-Integrin alpha V
YF-PA12787 50 ug
EUR 363
Description: Mouse polyclonal to Integrin alpha V
anti-Integrin alpha V
YF-PA12788 100 ug
EUR 403
Description: Rabbit polyclonal to Integrin alpha V
anti-Integrin alpha 6
YF-PA24004 50 ul
EUR 334
Description: Mouse polyclonal to Integrin alpha 6
anti-Integrin alpha 1
YF-PA24011 50 ul
EUR 334
Description: Mouse polyclonal to Integrin alpha 1
anti-Integrin alpha 4
YF-PA24013 50 ul
EUR 334
Description: Mouse polyclonal to Integrin alpha 4
anti-Integrin alpha 9
YF-PA24015 50 ul
EUR 334
Description: Mouse polyclonal to Integrin alpha 9
anti-Integrin alpha E
YF-PA24017 50 ul
EUR 334
Description: Mouse polyclonal to Integrin alpha E
Anti-alpha 5 beta 1 Integrin (Volociximab), Human IgG4 Antibody
A1092-200
EUR 729
Mouse Anti Human Integrin Alpha V Beta 5 Monoclonal Antibody
CABT-49626MH 0.1 mg
EUR 1375
Human Integrin Alpha 5 (ITGa5) ELISA Kit
DLR-ITGa5-Hu-48T 48T
EUR 498
  • Should the Human Integrin Alpha 5 (ITGa5) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Alpha 5 (ITGa5) in samples from tissue homogenates, cell lysates or other biological fluids.
Human Integrin Alpha 5 (ITGa5) ELISA Kit
DLR-ITGa5-Hu-96T 96T
EUR 647
  • Should the Human Integrin Alpha 5 (ITGa5) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Alpha 5 (ITGa5) in samples from tissue homogenates, cell lysates or other biological fluids.
Human Integrin Alpha 5 (ITGa5) ELISA Kit
20-abx151987
  • EUR 7112.00
  • EUR 3792.00
  • EUR 879.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
ELISA kit for Human Integrin alpha-5
EK4913 96 tests
EUR 670
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Integrin alpha-5 in samples from serum, plasma, tissue homogenates and other biological fluids.
Human ITGA5(Integrin alpha-5) ELISA Kit
EH2445 96T
EUR 567.6
  • Detection range: 0.156-10 ng/ml
  • Uniprot ID: P08648
  • Alias: ITGA5/CD49e/VLA-5 alpha/CD49 antigen-like family member E/CD49e/CD49e antigen/Fibronectin receptor subunit alpha/fibronectin receptor, alpha subunit/FNRAVLA5A/integrin alpha-5/Integrin alpha-F
  • Show more
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml
Human ITGA5/ Integrin alpha-5 ELISA Kit
E1342Hu 1 Kit
EUR 605
Human Integrin alpha- 5, ITGA5 ELISA KIT
ELI-07691h 96 Tests
EUR 824
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